What is Ampicillin + Sulbactam?
- Antibiotic
- Cat,
- Cow,
- Dog,
- Goat,
- Horse,
- Sheep
Active Ingredients: Ampicillin Sodium, Sulbactam Sodium
Ampicillin Sodium + Sulbactam Sodium for Injection is an antibiotic used to treat various types of bacterial infections in horses, livestock and companion animals. This medicine can be used as a parenteral alternative to amoxicillin + clavulanic acid or when oral treatment is not possible.
It is also preferable for the treatment of severe infections and prophylaxis. This combination drug contains two active ingredients: ampicillin sodium and sulbactam sodium.
Ampicillin is a broad-spectrum, beta-lactam penicillin antibiotic. It is effective against a wide range of gram-positive and gram-negative microorganisms.
Sulbactam sodium is a beta-lactamase inhibitor. It works to prevent the action of beta-lactamase, which destroys antibiotics like ampicillin. Sulbactam is typically only used parenterally due to its poor absorption within the GI tract.
This combination is effective against certain infections caused by Haemophilus influenzae, Escherichia coli, Acinetobacter, Klebsiella, Staphylococcus aureus, Enterobacter, and anaerobes. Depending on the preparation, this drug can be administered through an intramuscular or intravenous route.
It is important to note that this formulation of Ampicillin Sodium + Sulbactam Sodium for Injection is for veterinary purposes only. While Basil Hygiecare offers many similar products that are available for human use, this particular medication should be prescribed by a veterinary doctor or animal care specialist for an animal.
Ampicillin Sodium + Sulbactam Sodium for Injection is produced by Basil Hygiecare, a pharmaceutical company specializing in global distribution. Basil Hygiecare manufactures this veterinary medicine in GMP-certified factories located in China, India, and the USA. We routinely inspect these facilities to ensure our products meet health, safety, and environmental standards.
Why are we a trusted Ampicillin + Sulbactam manufacturer?
Basil Hygiecare is a leading GMP manufacturer of Ampicillin + Sulbactam Injection for veterinary use. Our company was established with the aim of providing excellent value to our veterinary distributors by concentrating on competitively priced, high-quality veterinary pharmaceuticals with market-tailored solutions.
Over the past 20 years, Basil Hygiecare has proven to be a trusted Ampicillin + Sulbactam manufacturer and supplier of 100+ veterinary injections in over 65 countries.
Precautions
Do NOT use Ampicillin Sodium + Sulbactam Sodium for Injection for an animal that: • has a known allergy or hypersensitivity to ampicillin or any other penicillin antibiotic.
Treatment with this drug should be administered with caution in an animal that:
- is hypersensitive to other beta-lactam antibiotics such as cephalosporins.
- is undergoing therapy with drugs such as probenecid.
- is being treated with aminoglycosides or bacteriostatic drugs like erythromycin or chloramphenicol.
- is pregnant or lactating.
- has renal failure.
Ampicillin may also cause a false positive result on a urine glucose test.
Uses
What is Ampicillin Sodium + Sulbactam Sodium used for?
It’s used to treat a wide range of bacterial infections such as:
- respiratory tract infections
- urinary tract infections
- skin and soft tissue infections
- bone and joint infections
What animals can be treated with Ampicillin Sodium + Sulbactam Sodium for Injection?
This medicine is recommended for horses and livestock like cows, goats, and sheep. It’s also used to treat companion animals like cats and dogs. Do not use Ampicillin Sodium + Sulbactam Sodium to treat rabbits, guinea pigs, chinchillas, hamsters, or other small mammals. It may cause enteritis or clostridial enterotoxemia in these animals.
How is Ampicillin Sodium + Sulbactam Sodium for Injection used?
This drug has been manufactured as a powder for reconstitution. The solution is relatively unstable and should be administered to the patient within 1 hour of reconstitution. This medicine can be administered either by the intravenous or intramuscular route.
How should Ampicillin Sodium + Sulbactam Sodium for Injection be stored?
This medication should be stored in a dark, dry location under 30°C.
What are the withdrawal times for Ampicillin Sodium + Sulbactam Sodium for Injection?
For cattle, the milk withdrawal time is 48 hours and the slaughter withdrawal time is 144 hours. Do not treat cattle for more than 7 days. Inform the veterinarian when the last time the animal was treated with this drug, so he can determine whether this drug can be used again.
Dosage
How much Ampicillin Sodium + Sulbactam Sodium should be given to cattle?
The usual dose is 5-10mg/kg, administered once or twice per day. The duration of treatment is 3-5 days.
How much Ampicillin Sodium + Sulbactam Sodium should be given to a dog?
For respiratory infections, the usual dose for dogs is 50mg/kg, given every 8 hours by IV. Alternatively, 20mg/kg can be given every 6-8 hours, IM/IV. For intra-abdominal infections, the usual dose is 20mg/kg, given every 6-8 hours IV/IM. For severe bite wounds (adjunct), the usual dose is 30-50mg/kg, given every 8 hours IV.
How much Ampicillin Sodium + Sulbactam Sodium should be given to a cat?
For respiratory infections, the usual dose for cats is 50mg/kg, given every 8 hours by IV. For intra-abdominal infections, the usual dose is 20mg/kg, given every 6-8 hours IV/IM. For severe bite wounds (adjunct), the usual dose is 30-50mg/kg, given every 8 hours IV.
Refer to a veterinary doctor or pharmacist for guidelines on dosage.
Side Effects
As with all pharmaceuticals, some unwanted effects can occur from the use of Ampicillin Sodium + Sulbactam Sodium for Injection.
Some common side effects may include but are not limited to gastrointestinal effects (appetite loss, vomiting, diarrhea).
Serious side effects may include:
- allergic reaction and anaphylaxis
- thrombophlebitis (when administered IV)
- neurotoxicity during long-term, high-dose treatment (in dogs)
Ampicillin Sodium + Sulbactam Sodium for Injection may cause pain when delivered intramuscularly.
For a comprehensive list of all possible side effects of this medication, consult a veterinarian.
